Fliban 100MG (Flibanserin)

Fliban 100MG is Centurion Laboratories Private Limited's flibanserin tablet, 100 mg, in a strip of 4 tablets. Flibanserin is a daily tablet for low sexual desire in women before the menopause, sold as Addyi.

Flibanserin is prescribed for premenopausal women with acquired, generalised hypoactive sexual desire disorder (HSDD): a lasting drop in sexual desire that causes distress and is not explained by a medical condition, a drug or a relationship problem.

Flibanserin acts on serotonin receptors in the brain, stimulating 5-HT1A and blocking 5-HT2A, which raises dopamine and norepinephrine and lowers serotonin in the circuits that govern desire. It is taken every day and takes weeks to work.

The usual dose is 100 mg once a day at bedtime, because of the risk of sleepiness and fainting. It should be stopped if there is no improvement after eight weeks. Follow your prescription and the pack leaflet.

• Dizziness, sleepiness and tiredness.
• Nausea, dry mouth and difficulty sleeping.
• Low blood pressure and fainting, especially with alcohol.

Alcohol raises the risk of severe low blood pressure and fainting. Current advice is to take the tablet at bedtime, to wait at least two hours after one or two standard drinks before taking it, and to skip that night's dose after three or more drinks. It must not be taken with moderate or strong CYP3A4 inhibitors (such as ketoconazole, clarithromycin, ritonavir, diltiazem or grapefruit juice) or with liver impairment. Not for postmenopausal women or men. Tell your doctor about other sedatives, antidepressants and oral contraceptives.